J. Appl. Poult. Res.
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J APPL POULT RES 2008. 17:278-282. doi:10.3382/japr.2007-00110
© 2008 Poultry Science Association
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Research Reports

Stabilization of Live Mycoplasma gallisepticum Vaccines During Vaccination with Second-Generation Spray-Vac Vaccine Stabilizer1

S. A. Leigh2, S. L. Branton and S. D. Collier

USDA, Agricultural Research Service, Mid-South Area Poultry Research Unit, Mississippi State, MS 39762

Correspondence: 2 Corresponding author: spencer.leigh{at}ars.usda.gov

Dilution and application of live Mycoplasma gallisepticum vaccines without the use of vaccine-stabilizing compounds may lead to significant loss of vaccine viability and loss of vaccine efficacy. Vaccine viability may decrease because of osmotic lysis of the mycoplasma as well as the presence of free chlorine or other detrimental chemicals in the water. Second-generation Spray-Vac vaccine stabilizer was developed and shown to maintain live Mycoplasma gallisepticum vaccine viability during exposure to free chlorine while protecting from the other factors that appear to decrease vaccine survival in solution. Increased vaccine survival in solution should lead to increased survival of the vaccine during vaccination. Field trial results demonstrate that second-generation Spray-Vac vaccine stabilizer yields excellent results without the need for distilled water or other vaccine-stabilizing compounds.

Key Words: Mycoplasma gallisepticum • vaccine • stabilizer • Spray-Vac

1 Mention of a trade name, proprietary product, or specific equipment does not constitute a guarantee or warranty by the USDA and does not imply its approval to the exclusion of other products that may be suitable.






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