J. Appl. Poult. Res.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J APPL POULT RES 2006. 15:229-235
© 2006 Poultry Science Association
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Teo, A. Y.-L.
Right arrow Articles by Tan, H.-M.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Teo, A. Y.-L.
Right arrow Articles by Tan, H.-M.

Research Reports

Effect of Bacillus subtilis PB6 (CloSTAT) on Broilers Infected with a Pathogenic Strain of Escherichia coli1

A. Y.-L. Teo and H.-M. Tan2

Kemin Industries (Asia) Pte. Ltd., Research and Development Department, 12 Senoko Drive, Singapore 758200, Republic of Singapore

Correspondence: 2 Corresponding author: haimeng.tan{at}kemin.com

In an attempt to demonstrate the efficacy of Bacillus subtilis PB6, isolated from the gut of a healthy chicken, on broiler performance, an experimental trial was conducted in which broilers, infected or uninfected with a pathogenic strain of Escherichia coli, were supplemented with B. subtilis PB6 (CloSTAT) or zinc bacitracin-colistin sulfate and compared against negative controls given no antibiotic supplementation. We observed 10- and 8-point improvements in feed conversion ratio (FCR) in 42-d-old uninfected broilers treated with B. subtilis PB6 when compared with the negative and antibiotic controls, respectively. However, infected birds supplemented with B. subtilis PB6 registered a significant 15-point FCR improvement over those in the negative control group (P < 0.05). Compared with the negative control, the increase in body weights of uninfected and infected 42-d-old broilers receiving B. subtilis PB6 were 97 and 152 g, respectively (P < 0.05). The growth-promoting and protective results from this study indicated that B. subtilis PB6 not only helped in the maintenance of beneficial bacteria but also could act as a replacement for antimicrobial growth promoters in broilers. The percentages of mortality of infected birds within antibiotic-treated groups and B. subtilis PB6-treated groups were reduced from 14% to 6 and 8%, respectively. Numerically, uninfected birds supplemented with B. subtilis PB6 had elevated levels of lactobacilli (1.4 to 4.5 x 107 cfu/g) in their intestinal tracts (32- and 42-d-old broilers) compared with the controls. Even after being challenged with a pathogenic strain of E. coli, the lactobacilli counts in the B. subtilis PB6-treated birds tended to remain the same as those receiving antibiotic and were considerably higher than those of the untreated birds.

Key Words: Bacillus subtilis • Escherichia coli • Lactobacillus spp. • antibiotic growth promoter replacement • feed conversion ratio

1 The use of trade names in this publication does not imply endorsement of the products mentioned or criticism of similar products not mentioned.




This article has been cited by other articles:


Home page
 J. Appl. Poult. Res.Home page
A. Y. Teo and H.-M. Tan
Evaluation of the Performance and Intestinal Gut Microflora of Broilers Fed on Corn-Soy Diets Supplemented With Bacillus subtilis PB6 (CloSTAT)
J. Appl. Poult. Res., January 1, 2007; 16(3): 296 - 303.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2006 by the Poultry Science Association.